Cannabis and Epidiolex
Weed Delivery Malibu — Why should THC be the only one having fun? Cannabidiol (CBD) is a compound in cannabis that doesn’t get you high. In 2018, the FDA gave Epidiolex approval to treat Lennox Gastaut syndrome and Dravet syndrome. It was the first CBD drug to get this approval. We know for sure that cannabis, and especially CBD, helps people with these severe and relatively rare types of epilepsy. In fact, it’s so safe that the FDA said it was okay for people with these two types of the disease who are at least 2 years old.
A 2020 meta-analysis published in the journal Frontiers in Neurology suggests that Epidiiolex may only be the beginning of clinical uses of cannabis to treat epilepsy. The researchers say that about a third of patients don’t respond to anti-seizure drugs, which makes CBD, which is always effective and doesn’t make people feel high, an appealing option. Most of the time, people get sick, have diarrhea, lose their appetite, or fall asleep. The researchers say that it is still not clear if CBD is good for other types of epilepsy. Long-term psychiatric and cognitive side effects, as well as the drug’s effectiveness and best doses for adults, also need to be figured out.
Oncology
A 2016 meta analysis in the Journal of Pain and Symptom Management found that 55 percent of people with cancer feel pain while they are being treated. Because opioid addiction is so common in the U.S., there is a pressing need for other ways to treat pain. According to a study in the 2020 Journal of Palliative Medicine, medical marijuana may help these patients.
There were 232 patients in the study. 95 of them did not use medical marijuana, and 137 did. All of them had prescriptions for opioids, which they all used at the same time. Pain and total ESAS (Edmonton Symptom Assessment System) scores went up for both groups. But only the people who used marijuana for medical reasons saw a statistically significant improvement in their emotional ESAS scores. Some other interesting results:
The number of people who used opioids went up by 23% among those who didn’t use medical marijuana, but it didn’t change among those who did. Those who used medical marijuana had no change in their pain symptoms, and their emotional symptoms got better. Those who didn’t use medical marijuana, on the other hand, had both pain and emotional symptoms get worse. Researchers came to the conclusion that “(medical marijuana) improved oncology patients’ ESAS scores even though opioid doses were lowered, and it should be considered a viable adjuvant therapy for palliative care.”
Common side effects of chemotherapy are also feeling sick and throwing up. A study by Health Psychology Research says that between 70 and 80% of patients have to deal with these annoying symptoms. Cancer Chemotherapy and Pharmacology published a meta-analysis in 2017 that suggests cannabis may help these patients. Researchers found that cannabinoids taken by mouth work as well as or better than traditional antiemetics. The problem is that different patients react differently to THC when they take an oral cannabinoid drug like dronabinol.
The pharmacokinetic variability between patients has gone down thanks to a new oral dronabinol solution. Another thing that makes things harder is that oral cannabinoids have more side effects than regular antiemetic drugs, like feeling dizzy, having a dry mouth, and falling asleep. At the very least, it might be helpful for oncologists to have this option for patients who don’t respond to regular antiemetics. Practice safe and responsible usage. And always talk with your doctor. Just a friendly reminder from Local Weed Delivery USA.